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Using Artificial Intelligence To Determine Patient Response To Immunotherapy

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Key Concepts:

  • While the current diagnostic strategies for PD-L1 checkpoint inhibitors identify some responders well, the majority of patients still need diagnostic approaches that better predict response.
  • PD-L1 IHC remains a valuable tool for predicting patient response, but can be limited by the ability to correctly use the test to interpret the complex underlying biology and response profile.
  • New IHC interpretation methods are capturing this biology and defining better patient selection tests, but the interpretations are complicated and hard for pathologists to implement.
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