The ability to identify each alveoli in a lung section, and then to measure statistics on each one is important in several lung-related therapeutic research area including inhalation toxicology and emphysema research. A custom algorithm has been developed where each alveoli is identified, and then perimeter and area can be calculated and the results graphed in a histogram. Some examples are below:
Lung section. Original image on the left, and markup image on the right, showing where a custom image analysis algorithm has identified each alveoli.
Area histogram on the left and perimeter histogram on the right, from each alveoli in the section above
2nd zoomed-in region showing individual detection and analysis of lung alveoli
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[...] are some examples, with the same Flagship fat algorithm that was used previously for white fat and lung alveoli. Image analysis results on brown fat measurements in liver Area and perimeter results per brown fat [...]
[...] Measuring individual lung alveoli across a tissue section This entry was written by Frank, posted on November 3, 2010 at 11:09 pm, and filed under IHC, large pharma, lung, oncology, small biotech. « A rating system for image analysis problems [...]