March 16, 2011 – 10:29 pm The novel staining approach combines the multiplexing capabilities of fluorescence with the tissue context of brightfield whole slide scanning FLAGSTAFF, Ariz. — March 17, 2011 — Flagship Biosciences announced today a novel whole slide imaging approach called Bridge Staining™, that allows a brightfield background to be aligned and overlaid on a fluorescent image on the same [...]
By flagship | Also posted in Multiplexed IHC, NEWS | Tagged autofluorescence, brightfield, chromagen, Dr. Frank Voelker, fluorescence scanning, fluorescent, fluorochrome, immunofluorescence, multiplexing, pathology, protein expression, tissue sections, visualization, whole slide imaging, whole slide scanning | January 23, 2011 – 3:31 pm In this example we use multimodal scanning of a brightfield stained slide in both brightfield and fluorescence to better delineate red from white pulp in spleen. The two images are overlaid with image registration, showing fluorescence scanning is better than brightfield for a more clear differentiation of red/white pulp. This aids in running more accurate [...]
January 5, 2011 – 2:54 pm Bridge Staining with Multimodal Scanning. In the images below each slide has been scanned once in brightfield and once in fluorescence, using dyes with multimodal scanning compatibility. The upper image is autofluorescence, in the lower image the DAPI has a very similar staining pattern to a fluorescence compatible hemotoxylin equivalent.
January 2, 2011 – 5:34 pm Whole slide fluorescence scanning of arteries to quantitate the tunica intima.